Prof. M. Helena Vasconcelos
Leader
IPATIMUP, Institute of Molecular Pathology and Immunology – University of Porto
The main goal of WG3 is the evaluation at a preclinical level of the efficacy of synthetic and natural compounds -and their formulations- developed by WG2. Compunds will be tested against the variety of samples (MDR cells lines, CSCs, primary samples derived from patients studied by WG1) in in vitro and in vivo; against the pro-invasive behaviour of MDR cells; on the activation of the host immune system against MDR tumors; and on the process of the intercellular transfer of the MDR phenotype by targeting proper biomarkers carried by MDR tumor-released microvesicles.
Information about WG3 meetings
Leader
IPATIMUP, Institute of Molecular Pathology and Immunology – University of Porto